In the presence and under the patronage of His Highness Sheikh Nahyan bin Mubarak Al Nahyan, Minister of Tolerance and Coexistence & the president of UAE Genetic Diseases Association, the MENA Organization for Rare Diseases Annual Meeting 2023 will be held in Dubai from 3 to 5 March 2023. This meeting will be the largest event for rare diseases in the region with more than 100 speakers. During this three-day meeting, experts will deliver the most updated knowledge in presentations and workshops related to rare diseases in various medical fields. The conference will particularly emphasize the latest advancements in research, therapeutics, and diagnostics related to rare diseases. In addition to healthcare providers, students, and researchers; individuals with rare disease and their families will participate by attending presentations, workshops, and meetings of families with rare diseases. Laboratories, pharmaceutical companies, clinics and hospitals, academic and community institutions, and several authorities and societies focusing on rare diseases will also participate. The ultimate goal of this meeting is to bring all parties involved in rare diseases in one place to connect and exchange knowledge aiming to increase awareness and provide better care for individuals with rare diseases.